Clinical Medicine × Computational Biomedical Science × Reliable AI
ResearcherBuilderVisual communicator

From clinical questions
to auditable evidence.

I am Yumo Chen, a Clinical Medicine student at Tongji Medical College, HUST. I study heterogeneous disease transitions through population data, causal inference, multi-omics, and single-cell analysis—and build AI research tools that keep claims traceable to their evidence.

Current research focus

Why elevated urate raises gout risk without producing a simple, universal molecular trajectory.

Olink proteomicsState transitionsSingle-cell
Explore research u202213428@hust.edu.cn
4published or accepted papers
2software copyright applications pending
6 + 2SCI manuscripts and NSFC proposals illustrated
2M+cross-platform impressions
01 · Featured research

A Two-Axis Model of Hyperuricemia and Gout

An independently led reanalysis that separates continuous urate-related risk from non-monotonic immune and clinical states.

Independent integrative reanalysis · manuscript in preparation

Does asymptomatic hyperuricemia sit on a simple molecular path to gout?

Higher and longer urate exposure raises future gout risk, but clinical conversion remains incomplete. I therefore tested a stronger molecular-continuum hypothesis rather than assuming it: if asymptomatic hyperuricemia were a simple intermediate stage, inflammatory proteins should rise monotonically from normouricemia to asymptomatic hyperuricemia and then gout. The current data reject that simple pattern and instead support a two-axis model—continuous urate-related risk alongside state-specific and heterogeneous immune programmes.

Olink proteomicsBulk RNA-seqPaired single-cell RNA-seqPatient-level pseudobulkCross-omics mappingR / Python
Primary Olink test0 / 73

proteins met the prespecified strict monotonic-increase criterion across normouricemia, asymptomatic hyperuricemia and gout.

State-specific signal14 proteins

were significantly enriched in asymptomatic hyperuricemia relative to both comparison states.

Bulk and paired single-cell datasets provide pathway context and cell-type localisation—not longitudinal proof or independent replication.

02 · Publications

Published and accepted work

Current authorship roles and contributions are stated explicitly; accepted work is labelled separately until its article page is available.

01

Acta Biomaterialia · 2025

Liquid metal-based biomaterials and flexible devices for injectable and implantable healthcare

Co-first author · created scientific figures and contributed to full-manuscript revision
02

Journal of Advanced Research · 2026

Immune cell dynamics in myocardial infarction: mechanisms, therapeutic targets, and translational perspectives

Co-first author · wrote and revised the multi-omics and translational sections, created figures and captions, and helped refine the manuscript structure
03

Journal of Nanobiotechnology · 2026

A continuous DNA repairing system for alleviating intervertebral disc degeneration

Co-author · contributed to cell and animal experiments, analysed staining results and prepared manuscript figures
04

Cell Reports · 2026 · Accepted

A USP28-BRD4 axis contributes to the acceleration of breast cancer growth by hyperglycemia

Co-author · contributed to cell and animal experiments, analysed staining results and prepared manuscript figures
03 · Research systems

Tools that remove friction from research and teamwork.

Four practical systems spanning evidence-grounded literature reading, hands-free experimental guidance, AI-assisted team coordination, and reproducible microscopy quantification.

Live system · open source

MedReader

A self-hosted medical-literature Agent that turns dense PDFs into a navigable, conversational and critique-ready knowledge base while keeping generated claims linked to source evidence.

  • Five synchronized panels: PDF, structured parsing, mind map, Agent Q&A and document outline
  • Six-dimensional analysis of questions, argument, methods/results, logic, novelty and limitations
  • Paragraph-level traceability, figure-aware reading and evidence-anchored follow-up questions
  • Next.js, TypeScript, Prisma/SQLite, MinerU, configurable LLMs and Docker Compose
Open live MedReader View source code
Live prototype · Rokid Glasses

LabGuide (Pip)

A hands-free wet-lab copilot that moves protocol navigation, reagent checks, timing and contemporaneous documentation into a voice-first workflow designed for smart glasses.

  • Voice-driven step navigation with pause, repeat, jump and resume controls
  • In-view reagent checklist, semantic timers and multi-stage alerts
  • Timestamped experiment annotations and structured report generation
  • Nine protocol families with RAG-grounded guidance across device, workflow platform and FastAPI backend
Explore LabGuide

Experimental-assistance prototype; not a medical device and not intended for diagnostic use.

In development · WeChat Mini Program · 2026

TeamSec

An AI secretary for 3–10 person teams, designed to absorb the scheduling, task coordination, progress tracking and project-review work that small teams rarely have dedicated staff to manage.

The current build contains the mini-program interface and cloud-function business logic. AI and speech recognition still use mock services while production APIs and the WeChat Cloud environment are being connected.

Find a timePersonal and team calendars, availability matching and meeting recommendations.
Turn discussion into actionMeeting transcription, structured task extraction and confirmation before dispatch.
See delivery risk earlyMilestones, workload, dependencies, weighted progress and delay warnings.
Ask the team secretaryNatural-language coordination across projects, tasks, meetings and the knowledge base.
ImageJ/Fiji macros · batch-ready

IHC + IF Quant

A pair of reusable microscopy-analysis macros that turns a repetitive, menu-driven workflow into a consistent route from image processing to analysis-ready results.

  • IHC: H-DAB colour deconvolution, staining stratification, H-Score and IRS in one run
  • IF: DAPI-based nuclei segmentation plus positive-cell percentage, intensity and positive-area metrics
  • Folder-scale use through Fiji's batch macro runner, with results accumulated in a single table
  • Explicit, editable thresholds preserve experimental control and make the workflow easy to audit
H-ScoreIRS 0–12Positive cellsIntegrated densityPositive area

Research-use workflow; parameters require calibration for each acquisition and staining protocol.

Representative immunohistochemistry image used in the ImageJ macro workflow
From image to statisticsReproducible · editable · reusable
04 · Scientific illustration

Scientific ideas, drawn clearly.

Selected Adobe Illustrator figures from my co-first-authored review on immune-cell dynamics in myocardial infarction.

Graphical abstract showing immune-cell dynamics in myocardial infarction
Graphical abstract

Discovery, immune-cell evolution and translational therapeutics across the myocardial-infarction continuum.

Adobe Illustrator · Journal of Advanced Research, 2026
Temporal-spatial multi-omics map of myocardial infarction
Temporal–spatial multi-omics map

Single-cell, spatial, proteomic and metabolic evidence organised around cardiac niches and time.

Adobe Illustrator
Conventional immunomodulatory strategies after myocardial infarction
Conventional immunomodulation

Cell-type-specific therapeutic strategies spanning B cells, T cells, macrophages and innate immunity.

Adobe Illustrator

The three scientific illustrations accompany “Immune cell dynamics in myocardial infarction”

05 · Research recognition

Recognition built through hands-on research.

Selected honours from basic-medical-science, experimental-design, biomaterials and undergraduate research programmes.

01

2025 · Grand Prize

National Undergraduate Basic Medical Sciences Innovation Forum & Experimental Design Competition

Team leader · also recognised for academic presentation, poster, team performance and showcase.
02

2025 · Provincial Second Prize

National Undergraduate Medical Innovation Competition

Team leader · TSC22D3 in diabetes-associated breast-cancer progression.
03

2025 · National Third Prize

National Undergraduate Biomaterials Design Competition

Team leader · biomimetic targeted-delivery nanoreactor for tumour immune-microenvironment remodelling.
04

2025 · Excellent Completion

National Undergraduate Innovation & Entrepreneurship Training Programme

Principal student investigator · p53 regulation of BRD4 in hepatocellular carcinoma cells.
05

2024 · Second Prize

National Undergraduate Basic Medical Sciences Innovation Forum & Experimental Design Competition

Team leader · additionally recognised as an Excellent Team.
06

2024 · Second Prize

Wuhan Innovation Method Competition

Research and innovation-method competition.
06 · Science communication

Research, made worth following.

Two complementary media brands translate biomedical ideas into long-form narratives and platform-native educational content.

BioRhythm logo
WeChat public account

BioRhythm

A Chinese-language science publication combining human-centred storytelling with rigorous biomedical evidence—covering the history, controversies, methods and emerging frontiers of life science.

Great PhysiciansResearch MisconductComputational MedicineOmics ToolboxEpidemiology StoriesCNS Weekly
Follow on WeChat
~4,000WeChat subscribers
MaoMao and Xiaofu orange cat avatar
Xiaohongshu · TikTok · Bilibili

MaoMao & Xiaofu

A cross-platform creator brand producing approachable medicine, research and study content—from visual explainers and literature stories to practical learning guidance.

10,000+followers across platforms
2,000,000+cumulative impressions

One editorial idea, adapted to the language, pacing and visual grammar of each platform.

View Xiaohongshu profile
07 · Personal writing

Learning to observe before explaining.

Beyond research writing, I have kept a long-form Chinese essay practice across travel, memory, education, film and everyday life.

Essays · Journeys · Reflections

Measuring the World

Written by Yumo Chen
2018 — 2025

Measuring the land in footsteps,
and growth in words.
A long-form personal archive

A medical student's record beyond the clinic.

From school corridors and changing years to southern cities, the Tibetan Plateau and rural classrooms, these essays document a way of understanding the world through attention, movement and language.

40+essays
≈105kChinese characters
5thematic volumes
20+cities observed
YearsJourneysPeopleDreams & FilmEveryday Life
Journeys

In Search of Tibet · Everest

“When the moon appears, she quietly carries the sun's whispers to the peaks, until the cold night breaks into dawn.”

People

Zhangjiaji · Everyday Life

In a rural classroom, teaching becomes a way to look at children—and at one's own beginnings—without distance.

Dreams & Film

The Vanished Noodle Shop

A quiet piece of fictionalised observation about absence, illness, family and the places that disappear with people.

08 · Personal art

Procreate studies.

Personal digital illustration exploring botanical form, restrained colour and traditional Chinese composition.

Procreate illustration of daffodils
Daffodil · digital study
Procreate illustration of magnolia and a bird
Magnolia and bird · digital study
09 · Beyond the desk

Movement, discipline, and the joy of play.

Tennis is a sustained part of my life beyond medicine and research. I have also served as a teaching assistant during masterclasses led by Chinese tennis champions Zheng Jie and Li Ting.

Yumo Chen with Zheng Jie at a tennis masterclass
2024 · Tennis masterclass

Zheng Jie

Former world No. 15 and a Wimbledon singles semifinalist. Teaching assistant during the V-level MVP tennis masterclass.

Yumo Chen with Li Ting at a tennis masterclass
2025 · Tennis masterclass

Li Ting

2004 Athens Olympic women's-doubles gold medalist. Teaching assistant during the Mercedes-Benz tennis masterclass.

I value tennis for the same habits I bring to research: repetition, concentration, adjustment under pressure and respect for the person across the net.